Cyclosporin A 

CAS：59865-13-3

Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.

Commonly used for the prevention of rejection reactions in various tissue and organ transplants and the treatment of some immune diseases, it is also used for kidney disease, aplastic anemia, and refractory ulcerative colitis. In dermatology, the most effective treatment for stubborn and refractory skin diseases is severe psoriasis (including common type, pustular type, erythroderma type, and joint disease type); Skin diseases with good therapeutic effects include Behcet's disease, pyoderma gangrenosum, lichen planus, and acquired epidermolysis bullosa; Diseases with moderate therapeutic effects include alopecia vulgaris, atopic dermatitis, chronic actinic dermatitis, actinic Chemicalbook like reticulocytosis, adult linear IgA bullous dermatitis, pemphigus, and bullous pemphigus (the latter two diseases need to be used in combination with glucocorticoids). In addition, cyclosporine is also effective for systemic lupus erythematosus, dermatomyositis, systemic scleroderma, AIDS, ichthyosis, cutaneous T-cell lymphoma, pityriasis rubra pilaris, generalized absent acrodermatitis, palmoplantar pustulosis, male alopecia, vitiligo, progressive necrotizing xanthogranuma, generalized granuloma annularis, mucoedematous lichen, papular mucinosis, hyperthyroidism, etc.